Depo-Provera and Brain Tumor Risk: What You Need to Know

Recent research has shown a possible connection between the use of Depo-Provera, a popular birth control shot, and an increased risk of brain tumors, specifically meningiomas.

Meningiomas are typically non-cancerous tumors that form in the protective layers of the brain and spinal cord. Although non-cancerous, these tumors can still cause serious health problems such as headaches, seizures, and vision issues.  In many cases, doctors will need to perform surgery to remove the tumor.  This surgery also carries risk of damage to functions controlled by the brain in the site surrounding the tumor.

The research found that women who used Depo-Provera or its generic versions for extended periods were at a higher risk of developing meningiomas. This risk increases with long-term use, making it important for women using this form of birth control to be aware of the potential dangers. The increased risk is thought to be linked to medroxyprogesterone acetate, a hormone in Depo-Provera that may stimulate tumor growth in sensitive brain tissues.

If you are taking Depo-Provera now and are considering stopping due to concern regarding the risk for a brain tumor, you should first speak with your prescribing doctor.

Should You Pursue A Depo-Provera Lawsuit?

If you or a loved one has been diagnosed with a brain tumor after using Depo-Provera, you might be able to receive compensation through a lawsuit. Mctlaw is investigating these claims for people who meet the following conditions:

  • PC must have been prescribed and had at least two injections of Depo-Provera or Depo-SubQ or a generic version of Depo-Provera (medroxyprogesterone acetate)
  • PC must have received the Depo birth control shot after 1992
  • PC must have been diagnosed with Meningioma (malignant or benign) or any other non-cancerous brain or spinal cord tumor or Pseudotumor Cerebri, also known as Idiopathic Intracranial Hypertension
  • PC must have used one of the qualifying injections for at least 12 months

AND

  • If they used a qualifying injection for 1 to 3 years, the diagnosis must be within 12 months of the last exposure

OR

  • If used qualifying injection for more than 3 years, diagnosis can be anytime after 12 months of exposure

If you meet these criteria, reach out to our legal team right away to discuss your case. There may be time limits on how long you have to file a claim, so don’t delay in seeking a free consultation.

Current Status of Depo-Provera Brain Tumor Litigation

As of October 2024, the Depo-Provera brain tumor litigation is still in its early stages.

  • No coordinated proceedings yet: There is no established multidistrict litigation (MDL) for these claims.  (Note that an MDL and a “Class Action” both coordinate large numbers of cases, but an MDL is generally better for cases where there is physical injury).  
  • No settlements or verdicts have been reached in the United States.
  • Ongoing Investigations: Lawyers are actively investigating and accepting new cases from people diagnosed with brain tumors, particularly meningiomas, after using Depo-Provera or its generic versions.
  • Lawsuits Against Pfizer: The lawsuits primarily focus on product liability claims against Pfizer, the manufacturer of Depo-Provera, for allegedly failing to warn consumers about the increased risk of brain tumors with prolonged use.

Why Choose mctlaw for Depo-Provera Lawsuits?

The attorneys at mctlaw have extensive experience handling complex product liability cases, including those involving defective medical devices and harmful drugs.

With a strong track record of successful verdicts and settlements, mctlaw is uniquely qualified to represent clients in Depo-Provera lawsuits.

The firm’s expertise in managing large-scale pharmaceutical litigation, combined with a national presence and a team of skilled attorneys, makes mctlaw a reliable choice for individuals harmed by Depo-Provera.

Timeline of Depo-Provera Brain Tumor Litigation

  • March 2024: A study published in The British Medical Journal linked Depo-Provera to a higher risk of meningioma.  The study was merely observational – it did not draw a cause-and-effect relationship.   However, it noted the importance of further research given their findings. 
  • March 2024:  Pfizer acknowledged the publication and stated: “We are aware of this potential risk associated with long-term use of progestogens and, in collaboration with regulatory agencies, are in the process of updating product labels and patient information leaflets with appropriate wording.”
  • August 2024: Lawyers began filing individual lawsuits and investigating claims. There is no centralized MDL for these claims yet.
  • October 2024: Litigation remains in the preliminary stages, with no reported settlements or trial outcomes so far.

Risks of Using Depo-Provera Compared to Other Birth Control Methods

A study published in The British Medical Journal in March 2024 found that women who used Depo-Provera had a 5.6 times greater risk of developing meningiomas compared to women who used other hormonal contraceptives.

This elevated risk is particularly concerning for long-term users. Plaintiffs in these lawsuits argue that if Pfizer had disclosed this information, many women would have chosen different contraceptive options, and healthcare providers would have been more careful when prescribing the drug.

If you believe you have a claim related to Depo-Provera use, contact the attorneys at mctlaw right away for a free consultation. They will review your case based on your medical history, length of Depo-Provera use, and your diagnosis to determine if you qualify for compensation.

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Content Reviewed by Ilyas Sayeg – Product Liability Lawyer

MCTLaw attorney Ilyas Sayeg

Ilyas Sayeg is a partner at mctlaw working in the Firm’s product liability and complex consumer protection practices representing clients with failing metal on metal hip replacements and recalled Exactech hip and knee implants. Mr. Sayeg represents “Davids” nationwide who are injured by defective products and deceptive business practices of the corporate “Goliaths” who put profit before safety. A passionate advocate, he takes pride in standing toe-to-toe against some of the largest companies in the world to help his clients seek justice. Mr. Sayeg is a member of the American Association for Justice.

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