Ileal Obstruction from Ozempic

There is growing concern that medications like Ozempic, Trulicity, Wegovy, Mounjaro, Rybelsus and similar GLP-1 drugs, may increase the risk or cause severe intestinal blockages.

Risk of ileus or intestinal obstruction

The ileum is the last part of the small intestine and connects to the large intestine. Paralytic ileus happens when the ileum becomes blocked, preventing food, liquids, and gas from moving through the digestive tract into the large intestine. 

GLP-1 medications may contribute to this by slowing down digestion. When digestion is slowed, food can accumulate in the intestines, which can increase the risk of a blockage. 

An ileus or intestinal obstruction is a serious life threatening injury that needs immediate medical attention. Complications from a bowel blockage can include:

  • Sepsis
  • Bowel tears
  • Kidney failure
  • Death

FDA Report of reactions to Ozempic, Trulicity, Wegovy, Mounaro and Rybelsus

There have been more than 130,000 adverse reactions reported to the FDA after taking GLP-1 medications, based on data from the the FDA Adverse Events Reporting System (also called FAERS). 

Almost 40,000 of those reactions involved gastrointestinal issues, including reports of intestinal obstruction, small intestinal obstruction, paralytic ileus, gastric obstruction, and intestinal perforation.

How Ozempic and Similar Medications Affect Digestion

Ozempic, Trulicity, Wegovy, Mounjaro and Rybelsus work by mimicking the hormone glucagon-like peptide-1 (GLP-1), which slows down food moving from the stomach to the intestines. 

This delayed movement of food through the digestive tract can lead to gastroparesis, which can  cause a buildup of food in the intestines, increasing the risk of an obstruction.

Symptoms of ileus obstruction or bowel obstruction

According to the Mayo Clinic, the most common symptoms of an ileus or bowel obstruction are:

  • Cramping abdominal pain
  • Loss of appetite.
  • Constipation
  • Vomiting
  • Inability to have a bowel movement or pass gas
  • Swelling of the abdomen

Why mctlaw Should Represent You in a Gastroparesis Lawsuit Against the Makers Ozempic, Wegovy, Mounjaro, Trulicity and Rybelsus.

  • We put our clients first. We always do what’s best for our clients.
  • Our Firm knows how to hold large product corporations accountable to pursue the compensation you deserve.
  • We have the financial resources to support your case for as long as it takes. 
  • We believe our clients deserve the highest possible award or settlement and we will fight for that.  
  • We are selective in the cases we represent. That means we can negotiate a settlement from a position of strength for our clients or confidently take a case to trial.

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Content Reviewed by Michele Stephan – Product Liability Lawyer

Michele Stephan

Michele Stephan handles product liability cases in state and federal courts throughout the country. Ms. Stephan has represented clients in civil litigation for over 25 years.  At mctlaw she litigates cases for clients with defective hip replacements and defective drug and pharmaceutical lawsuits. Ms. Stephan is a member of the Twelfth Judicial Circuit Pro Bono Committee and a Director of the Sarasota County Bar Association.

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